With the support of the UCLA/UCSF Adverse Childhood Experiences (ACEs) Aware Family Resilience Network (UCAAN) and the Olive View-UCLA Education and Research Institute, the UCLA Pritzker Center has partnered with the ACEs-LA Network of Care to produce a series of policy briefs on the implementation of ACE screening and response activities to prevent and address the impact of childhood adversity and toxic stress within pediatric clinics across Los Angeles County.  Findings from four standalone analyses – on topics ranging from Enhanced Care Management eligibility to the effectiveness of mindfulness meditation on youth anxiety and depression–  highlight use of ACE screening as a tool with potential to improve care for those at highest risk of toxic stress. The briefs also underscore a need for increased training policy makers, MCOs, healthcare providers on the impact of ACEs and toxic stress, in order to enhance the use of existing trauma-responsive services available to children and families through California Advancing and Innovating Medi-Cal (CalAIM).